Who We Are
Clinvet is a global veterinary contract research organization (CRO) that conducts in vitro, preclinical, and clinical trials to evaluate animal health products’ safety, metabolism, and efficacy.
We also offer field and laboratory pesticide efficacy testing to the chemical and public health industries.
Clinvet is part of the Clinglobal group – an animal health-focused group of CROs dedicated to supporting innovation and product development.
With a wealth of research experience, Clinvet has supported leading global animal health companies, small and medium-sized companies, and start-ups with their research and development programs since 1999.
What We Do
- Clinical and preclinical trial support
- Clinical and preclinical trial conduct (Animal and Public Health)
- In vitro testing and screening
- Extensive portfolio of research models in production and companion animals
How We Work
Clinvet is part of the Clinglobal group of partner companies.
Clinglobal provides a platform of support services, resources, systems, and processes that ensures our customers have the best possible experience. This unique model leverages the capabilities of our sites, the other companies in the group, and the expertise of our renowned scientists and product development consultants.
Our model ensures scalability and economies of scale, allowing the resources of each partner company to be assigned by function, focusing on key competencies.
Clinvet sites have dedicated staff to efficiently provide high-quality study services at each research facility.
Ready To Work With Us? Get In Touch
Services
- Clinomics
- An R&D laboratory that supports preclinical and clinical studies with molecular, serological, hematology, and biochemical diagnosis and has a track record of new molecular and antibody-based test development.
- Rtilab
- An R&D microbiology and immunology laboratory that provides preclinical and clinical studies solutions and serves the animal health, food, feed, and agriculture industries with diagnostics and quality control services.
Clinical Trial Support
We conduct clinical and preclinical studies and provide the following support services through our partner companies:
- Clindata
- Data management (EDC/Paper)
- Risk-based monitoring support
- Medical coding
- Data capture form (DCF) and electronic case report form (eCRF) design
- In vitro testing and screening
- Database design, edit check programming, and validation
- Biostatistics and statistical programming
- Regulatory submission preparation
- Clinglobal
- Monitoring
- Project and Programme management
- External laboratory selection, qualification, and monitoring
- Quality Assurance (system, process, qualification, study-specific audits)
- Scientific writing (protocol, report, and publications)
- Document management for regulatory submissions
- Regulatory support/Strategy
Animal Health Research
We offer pharmaceuticals, biologicals, biopharmaceuticals, feed additives, and other products’ efficacy, safety, and metabolism studies for animal health.
Frequently used animal models include rats, rabbits, cats, dogs, goats, sheep, cattle, pigs, poultry, and horses. We offer the following types of studies:
- In vitro and in vivo screening
- Proof of concept
- Dose determination and confirmation
- Parasite challenge (both artificial/laboratory and natural)
- Vaccine challenge and duration of immunity
- Bacteriological challenge
- Bioequivalence
- Pharmacokinetics/Pharmacodynamics
- Residue depletion
- Target animal safety
Public Health Research
We propose the following types of studies for rodenticides, pesticides, and repellency products typically used by the general public:
- In vitro testing
- Insecticide testing
- Repellence testing
- Rodenticide testing (both laboratory and field)
Studies are conducted according to appropriate guidelines (e.g., EU TNsG for PT 18 and PT 19; DAFF Guidelines for the Registration of Household Agricultural Remedies; WHO Guidelines; EPA OTTP Guidelines and OECD Environmental Directorate Guidelines).
New models can be developed on request.
In Vitro & In Vivo Screening
In vitro assays include contact and repellency bioassays and artificial feeding models and systems.
Contact assays (like LPT, LIT, and AIT) and repellency tests use direct exposure of the parasites to an active ingredient, either in solution or on filter paper, glass, or other materials.
In artificial feeding assays, systemic compounds can be tested by allowing blood-feeding ectoparasites (like sandflies, mosquitoes, and ticks) to feed on treated blood or another media across a synthetic membrane or by allowing endoparasites to move through a medium and assessing their behavior.
Small animal models against ecto- and endo-parasites are also feasible.
Production Animal Models
Clinvet sites and our partner sites perform research projects on numerous parasites and infectious diseases affecting bovine, ovine, caprine, swine, equine, and poultry. These projects are conducted in the field or within containment facilities in Africa and the USA. Depending on the biosafety requirements for the specific pathogen, animals can be housed in up to ABSL2+ facilities.
Visit our list of research models through the link below, and contact us for any models of interest that are not listed. We will be more than willing to develop these in partnership with our customers.
Companion Animal Models
Clinvet has developed parasitic and infectious disease models to conduct studies in the field or our containment facilities in Africa or the USA. Depending on the biosafety requirements, animals can be housed in groups or individually in up to ABSL2+ facilities.
Visit our list of research models through the link below, and contact us for any models of interest that are not listed. We will be more than willing to develop these in partnership with our customers.
Haemoparasite, Arthropod & Helminth Breeding
We maintain a vast bank of companion and production animal parasites and arthropods with representative species and strains from the USA, Europe, Asia, and Africa for efficacy challenge studies.
- We offer efficacy studies on:
- 15 species of ticks (23 different isolates)
- 1 species of fleas (4 isolates)
- 16 species of helminths (22 isolates)
- 3 species of flies
- 3 species of mosquitoes
- 4 species of mites
- 2 species of lice
- 6 species of haemoparasites
Laboratory Services
Located within the Clinvet South Africa facility, Clinomics is an R&D laboratory that supports preclinical and clinical studies with molecular, serological, hematology, and biochemical diagnosis and has a track record of new molecular and antibody-based test development.
Rtilab is an R&D microbiology and immunology laboratory that provides solutions for preclinical and clinical studies and serves the animal health, food, feed, and agriculture industries with diagnostics and quality control services. Rtilab is located within the Clinvet South Dakota site.
Meet The Team
Marna Naude, BVSc; MSc
Clinvet South Africa SITE DIRECTOR
A veterinary surgeon with a MSc in Veterinary Epidemiology, Dr Naude has had a diverse career working in the South African Government sphere as a State Veterinarian and in a research environment at the Colorado State University (USA), before joining Clinvet in 2015. In her role as Site Director since 2019, she oversees all facets of operations with a steadfast commitment to scientific excellence, regulatory compliance, and animal welfare.
Julian Liebenberg, MSc
Clinvet South Africa DIRECTOR: RESEARCH OPERATIONS
Mr. Liebenberg has been researching veterinary medicines for more than 15 years, acting as a Study Director and/or Investigator on more than 300 studies, mainly focussing on parasitology. He manages the research teams at Clinvet South Africa, overseeing all research projects and is involved in parasiticide program development for EU and US registrations. He is also active in the scientific arena and the co-author of over 30 scientific papers.
Josephus Fourie, PhD
Clinvet US (NEW YORK) SITE DIRECTOR
Dr. Fourie has been researching veterinary medicines for more than 20 years. Active in the scientific arena and the co-author of over 75 scientific papers and guidance, two book chapters, and a two-volume book series on parasiticide screening in vitro and in vivo tests, Dr Fourie oversees the group’s research operations worldwide.
Tayna Shaffer, AAS, RN, LAT
Clinvet US (New York) DEPUTY DIRECTOR: RESEARCH OPERATIONS
A Registered Professional Nurse and Laboratory Animal Technician, Tayna joined the animal health industry in 1998. Her experience includes Study Director/Investigator and technical roles on GLP, GCP and Non-GLP/GCP studies as well as IACUC, IBC and Safety Committee memberships. Tayna also has over 15 years of site and technical staff management.
Nawfal Hdadech, DVM
Clinvet Morocco SITE DIRECTOR
With over 15 years of experience in animal and public health, Dr. Nawfal Hdadech has honed his expertise in disease prevention and control as a Lab Manager in the meat industry and a mandated practitioner in national prophylaxis against notifiable diseases. In 2017, Dr. Hdadech joined the Clinvet team as the attending veterinarian, before shifting his focus to Facility Management and Biosafety. Since 2022, as Site Director, he oversees all operations with an unwavering dedication to animal welfare and regulatory compliance.
Imad Bouzaidi Cheikhi, MSc
Clinvet Morocco Senior Manager: Research Operations
After completing an MSc in Microbiology and virology from the Scientific and Technic University in Morocco and a second MSc in Proteomics from the Nancy University in France, Imad acquired multiple experiences in research, diagnostics, and drug development across a variety of fields. In 2018, Imad started working in the research department at Clinvet Morocco and his career developed from a laboratory manager role into his current position as the Senior Manager of the Research Operations Department in Clinvet Morocco, managing the Research operations department, including study management and laboratory services and overseeing all projects.
Chris Chase, DVM, PhD
Clinvet South Dakota CHIEF SCIENTIFIC OFFICER
Dr. Chase co-founded RTI, LLC in 1994, realizing a niche for a quality contract research organization in Brookings, SD, by taking advantage of the resources and graduates of nearby South Dakota State University. His expertise in animal disease research allows him to integrate veterinary research with the practical aspects of clinical medicine to provide direction in protocol development.
Thomas Williams,
Clinvet South Dakota SITE DIRECTOR
Tom Williams assumes the site director role of ClinVet SD after joining the ClinVet team in February 2022 to manage and decommission a remote site prior to his relocation to Brookings SD. A graduate of Fresno State, CA with a degree in Animal Science, Tom brings with him over 20 years of successful research experience in academic, CRO and private industry. During his career he has worked with both production and companion animals, with experience in reproduction, nutrition, biologic and pharmaceutical research. He has also gained management experience across a variety of facilities throughout his career, and is excited to bring his fair and honest approach to providing exceptional quality and customer support
